PT-141 goes by two names, which trips people up. PT-141 is the research shorthand, and bremelanotide is the same molecule. It belongs to a different family than the metabolic peptides in this series: instead of incretin receptors, it works on the melanocortin system. That is where all of its research interest sits.
What is PT-141?
PT-141, also called bremelanotide, is a synthetic peptide that acts as an agonist at melanocortin receptors. It is a cyclic peptide, and it is structurally related to an earlier melanocortin compound from which it was derived. Its CAS number is 189691-06-3 and its molecular formula is C50H68N14O10. Like the other compounds we cover, it is made by solid-phase synthesis and defined by its certificate of analysis rather than by its name.
The melanocortin system
Melanocortin receptors are a family of receptors involved in a range of signaling processes, from pigmentation to neurobehavioral pathways. PT-141 is studied as a tool for probing these receptors, particularly the subtypes tied to central signaling. Because the melanocortin family has several members, a recurring research question is how selectively a given agonist acts across them.
How is PT-141 studied?
In the laboratory, PT-141 appears in work on:
- Receptor binding: how the peptide interacts with melanocortin receptor subtypes.
- Signaling pathways: models of the downstream activity these receptors trigger.
- Neurobehavioral models: research on central melanocortin signaling in animal systems.
These are preclinical, model-based studies. PT-141 is supplied strictly as a research compound, and nothing here describes use in people or animals.
Handling and verification
PT-141 is a cyclic peptide, so confirming its identity matters as much as its purity. It is checked by HPLC and mass spectrometry, ships lyophilized, and comes with its certificate of analysis. Any Codex Research vial can be confirmed by its batch number.
Research use only
All products sold by Codex Research, including PT-141, are strictly for laboratory research and development. They are not for human or animal consumption and are not intended to diagnose, treat, cure, or prevent any disease.
The compound at Codex Research
PT-141, 10 mg per vial — batch-verified, with its certificate of analysis.
Frequently asked questions
Are PT-141 and bremelanotide the same thing?
Yes. PT-141 is the research shorthand and bremelanotide is the same synthetic peptide. It is a melanocortin receptor agonist used strictly for laboratory research.
What receptor does PT-141 act on?
PT-141 acts as an agonist at melanocortin receptors, a family involved in signaling processes including pigmentation and central neurobehavioral pathways. Research often focuses on how selectively it acts across the receptor subtypes.
How is PT-141 verified for research?
Each batch is tested by HPLC for purity and mass spectrometry for identity and ships with a certificate of analysis. Codex Research vials can also be checked by batch number at codexresearchlab.com/verify/.